High Purity 99% Tolvaptan CAS 150683-30-0 for Hyponatremia

Tolvaptan Profile

CAS: 150683-30-0 

Purity: 99% min

Appearance: white solid 

MF:C26H25ClN2O3

MW:448.94

Purity: 99%

Boiling point :219-222°C

Flash point :198.2

Refravtive index :1.58

Appearance:white to off-white crystalline powder

Grade: Pharmceutical Grade

Place of Origin:Wuhan, China

Lead time:1-2 days upon receipt of payment

Delivery time:Usually 4-6 working days by air

Standard: enterprise Standard

Storage: Shading, confined preservation

Usage : intermediate for Lornoxicam

Purity:99%

Package:25kg/barrel or as your inquiry

Shelf life:2 years

Standard:Enterprise Standard 

Price:negotiable 

MOQ:10g

Specification:ISO9001,USP,BP

Trade Mark:CQSP

Port:Shenzhen/Shanghai,China

Production Capacity:5000kg/month

Shipping: FedEx, DHL, EMS, TNT, HK EMS, Eub, Etk

Payment: Western Union, Moneygram, T/T, Bitcoin

Delivery time: Parcel can be sent out within 24 hours after payment,4-7days to arrive.

Usage and dosage

Pharmacology and toxicology: a vasopressin V2 receptor antagonist (non-peptide AVP2 receptor antagonist), can increase plasma sodium concentration, to help excess water from the urine. Enhance the ability of the kidney to treat water. Polycystic kidney cells within the cyclic adenosine monophosphate (cAMP) accumulation, which by stimulating cyst fluid secretion and lined cell proliferation to promote cyst growth. Tovatan is a type 2 vasopressin receptor antagonist that inhibits cAMP production and accumulation. In a variety of PKD animal model studies, tolvaptan showed good efficacy.

Tolvaptan Indications

Indications: treatment of congestive heart failure, cirrhosis and inappropriate antidiuretic hormone secretion syndrome (SIADH syndrome) caused by hyponatremia.